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Letters to the Editor

Cardiac magnetic resonance imaging findings in COVID-19 vaccine-related myocarditis

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Page 308 | Received 29 Dec 2022, Accepted 18 Jan 2023, Published online: 27 Jan 2023

Dear Editor,

We would like to share ideas on the publication “Admission and follow-up cardiac magnetic resonance imaging findings in BNT162b2 Vaccine-Related myocarditis in adolescents [Citation1]. The goals of Özen et al. were to describe the myocardial damage brought on by BNT162b2 immunisation, to increase awareness of vaccine-related side effects, and to identify the patterns and extent of cardiac magnetic resonance imaging (MRI) findings [Citation1]. Nine patients with vaccine-associated myopericarditis were tracked by Özen et al. [Citation1]. To establish the clinical significance of persistent cardiac MRI anomalies, Özen et al. came to the conclusion that bigger multicenter investigations and more extensive follow-up evaluation are required [Citation1].

It is typically challenging to pinpoint the specific clinical association because there is little clinical information on the health and immunological status of vaccination recipients prior to injection. Comorbidities exist, however, they are infrequently discussed in published studies. There isn’t much data on the health and immunological status of vaccine recipients before to injection, making it occasionally difficult to pinpoint the precise therapeutic link. The patient’s comorbidities may have contributed to the problem. The potential for concurrent dengue infection, which could have clinical repercussions, is one intriguing example [Citation2]. There isn’t much data on the health and immunological status of vaccine recipients before to injection, making it occasionally difficult to pinpoint the precise therapeutic link.

The patient’s comorbidities may have contributed to the problem. Finding a precise clinical relationship can be difficult at times. Additionally, studies have shown that the inheritors’ genetic diversity affects immunological responses. According to a study [Citation3], genetic factors influence how people’s immune systems react to vaccinations. It is necessary to perform a test before choosing a choice. More research is necessary to rule out any additional exacerbating factors, such as co-morbidity or an underlying pathological condition. Furthermore, it is critical to consider any current or previous asymptomatic COVID-19 infections. Given how unusual the situation is, it could be a good idea to take it into account [Citation4].

Acknowledgments

We confirm that we have read the Journal’s position on issues involved in ethical publication and affirm that this report is consistent with those guidelines.

Disclosure statement

No potential conflict of interest was reported by the author(s).

References

  • Özen S, Kibar Gül AE, Gülhan B, et al. Admission and follow-up cardiac magnetic resonance imaging findings in BNT162b2 vaccine-related myocarditis in adolescents. Infect Dis. 2022:1–8. DOI:10.1080/23744235.2022.2157478
  • Kebayoon A, Wiwanitkit V. Dengue after COVID-19 vaccination: possible and might be missed. Clin Appl Thromb Hemost. 2021;27:10760296211047229.
  • Čiučiulkaitė I, Möhlendick B, Thümmler L, et al. GNB3 c.825c>T polymorphism influences T-cell but not antibody response following vaccination with the mRNA-1273 vaccine. Front Genet. 2022;13:932043.
  • Joob B, Wiwanitkit V. Letter to the editor: coronavirus disease 2019 (COVID-19), infectivity, and the incubation period. J Prev Med Public Health. 2020;53(2):70.

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