Development of a new methodology for the synthesis of chloro(glycinato)1,10-phenanthroline copper(II) monohydrate and analogous complexes and study of their catalytic utility towards selective hydroxylation of phenol

ABSTRACT

A new simple and convenient method has been developed for the synthesis of copper(II)complexes using Proline and Glycine as ligand. The complexes were characterized by using conventional spectroscopic techniques and by determining structure. Methodology developed gives substantial yield of the products. Chloro(Glycinato) 1,10-Phenanthroline Copper(II) monohydrate and other complexes effectively catalyze the selective orthohydroxylation of phenol, in presence of Hydrogen peroxide, in water. Catechol formation was confirmed by IR and NMR spectroscopy. Hydroxylation reaction produces moderate to good yield of the product catechol. Longer time duration results in decrease of yield.

KEYWORDS:

• 1,10-Phenanthroline
• Glycine
• Methodology
• Hydroxylation
• Phenol
• Catechol
• Regioselectivity

Funding

Author sincerely acknowledges Department of Science & technology, Government of India for financial support received under project grant (Project ID: DST / RFBR / P-221).