Fruit extract mediated synthesis of silver oxide nanoparticles using Dimocarpus longan fruit and their assesment of catalytic, antifungal, antioxidant and cytotoxic potentials

Abstract

The biosynthesis of nanoparticles has been proposed as a cost-effective and environmentally friendly alternative to chemical and physical methods. In the present study, the synthesis of silver oxide nanoparticles has been achieved using Dimocarpus longan fruit. The fruit extract can act as both the reducing agent and stabilizing agent. The synthesized silver oxide nanoparticles were characterized using UV-visible spectrometer the peak observed at 460 nm, FT-IR spectrum implies that polyphenolic compounds were responsible for the formation of silver oxide nanoparticles, XRD analysis, Scanning Electron microscope (SEM) shows poly dispersed nanoparticles and EDAX spectrum shows sharp peak at 3 KeV. The particle size range was found to be 30 to 123 nm and the stability calculated by Zeta potential was −25 mV. The prepared silver oxide nanoparticles were investigated for their catalytic activity on the reduction of p-nitrophenol(4-NP) to p-aminophenol(4-AP). The fruit extract of silver oxide nanoparticles was biologically active and exhibit antifungal activity. The antioxidant potential of silver oxide nanoparticles were investigated by DPPH assay and the IC₅₀ value was found to be 60 μgml⁻¹. The anticancer activity of silver oxide nanoparticles was determined using MTT assay against MCF-7 breast cancer cells.

Graphical Abstract

Keywords:

• Silver oxide nanoparticles
• Dimocarpus longan
• catalytic activity
• anticancer activity