Abstract
In the present work, the authors prepared nanocomposite cotton gauze cloth (NCGC) by in situ generating the nanoparticles of silver (ANPs) and copper (CuNPs) and their binary metallic nanoparticles (BMNPs) using aqueous extraction of Azadirachta indica leaves as a reducing agent. The NCGCs had roughly spherical AgNPs, CuNPs and BMNPs in the size range of 50–120 nm. The corresponding mean size of the spherical AgNPs, CuNPs and BMNPs was 94, 89 and 87 nm respectively. The participation of the hydroxyl and amino groups of the leaf extract in the generation of the metal nanoparticles in the NCGCs was established by studying the chemical interactions. All the NCGC specimens exhibited significant antibacterial activity. However, the NCGCs with BMNPs had higher antibacterial efficiency when compared to those with homo metal nanoparticles. Hence, the NCGC with generated BMNPs can be effectively used as antibacterial wound dressing material.
Acknowledgments
We hereby acknowledge and sincerely appreciate unalloyed supports from the managements of the following institutions: Osmania University, Hyderabad, India as well as the Kalasalingam Academy of Research and Education, Tamil Nadu, India. The King Saud University authors acknowledge the funding from Researchers Supporting Project (RSP-2021/355), King Saud University, Riyath, Saudi Arabia.
Declarations
Conflicts of interest
None.
Availability of data and material
The raw/processed data required to reproduce these findings cannot be shared at this time as the data also forms part of an ongoing study.
Code availability
Not applicable.
Author contributions
Basa Ashok: Collected primary data, contributed in draft, contributed to the analysis of data, checked the draft, and overall manuscript prepared and finalized the contents. M.P. Indira Devi: Contributed in writing. P. Sivaranjana: Contributed in writing. AnumakondaVarada Rajulu: Planned and executed the work and contributed in analysis of the results and writing. Faruq Mohammad: Contributed in writing. Sikiru Oluwarotimi Ismail: Contributed in writing. Hamad A. Al-Lohedan: Contributed in writing. Rajini Nagarajan: Supervised and contributed in writing.