A case of otitis media with ANCA-associated vasculitis accompanied with pituitary mass successfully treated by corticosteroids

Abstract

Otitis media with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (OMAAV) is a new disease entity characterized by progressive sensorineural hearing loss and intractable otitis media against antibiotics and tympanic tube insertion accompanied with ANCA positivity. A 65-year-old woman developed progressing hearing loss, saddle nose, and left facial nerve palsy accompanied with a non-functional pituitary mass and positivity for myeloperoxidase (MPO)-ANCA. She was diagnosed with OMAAV and probable granulomatosis with polyangiitis. Otitis media and hearing acuity were improved and the pituitary mass disappeared after a 40 mg/day course of prednisolone. This is a rare case of OMAAV accompanied with non-functional pituitary mass.

Keywords:

• Anti-neutrophil cytoplasmic antibody (ANCA)
• otitis media with ANCA-associated vasculitis (OMAAV)
• granulomatosis with polyangiitis
• pituitary mass
• facial nerve palsy

Acknowledgements

We thank Dr. Bryan J. Mathis of the Medical English Communications Center, University of Tsukuba, for critical review of this manuscript.

Conflict of interest

None.