Step by Step Modification of Electrospinning Process to Fabricate Ultra-Fine Dextran Nanofibers

ABSTRACT

Dextran ultra-fine nanofiber mats with uniform morphological appearance were fabricated using the electrospinning process. Increasing the solution concentration from 0.5 g.mL⁻¹ to 0.9 g.mL⁻¹ changed the fiber structure from coarse-beaded to a uniform beadless nanofiber mats. Additionally, reducing the feed rate from 1 mL.h⁻¹ to 0.25 mL.h⁻¹ with increasing the spinning distance from 150 to 170 mm generally led to a decrease in the diameters of the fibers. At the end; uniform dextran nanofibers with diameters ≈227 nm fabricated by the systematic modification of the electrospinning process. Crosslinked dextran nanofiber mats represent promising candidates for biomedical and tissue engineering.

KEYWORDS:

• Electrospinning technique
• dextran electrospun
• Ultra-fine nanofiber
• process variables
• morphological characteristics

Disclosure statement

No potential conflict of interest was reported by the authors.

Supplementary material

Supplemental data for this article can be accessed online at https://doi.org/10.1080/25740881.2022.2113895

Additional information

Notes on contributors

Hamed Salimi-Kenari

Hamed Salimi-Kenari received his PhD from Iran Polymer and Petrochemical Institute (IPPI) in 2012. He is currently Assistant Professor of the Chemical Engineering Department at University of Mazandaran, Iran. His research interests include fabrications of biopolymer-based micro- and nanostructures for various applications specifically preparations of biodegradable porous composite scaffolds for tissue engineering.

Mehdi Barari

Mehdi Barari received his MSC degree in Chemical Engineering from University of Mazandaran. His research is mainly focused on electrospinning of polymer nanocomposites and their application in tissue engineering.

Seyed Reza Nabavi

Seyed Reza Nabavi received his Ph.D. degree from the University of Tabriz in 2008. He joined the University of Mazandaran as an Assitant Professor in 2011. His research is now focused on the electrospun nanofibers and thier application in membrane separation process.

Atefeh Mousavi Anjeh

Atefeh Mousavi Anjeh has obtained MSC degree in Applied Chemistry from University of Mazandaran in the year 2018. Her research is mainly focused on electrospinning of polymer nanocomposites and their application in wastewater treatment.

Sayed Reza Hosseini

Sayed Reza Hosseini received his PhD from University of Mazandaran, 2012. He is presently working as Associate Professor at University of Mazandaran. His current interest includes on development of new electrochemical sensors, nanochemistry ,direct alcohol fuel cells and electrospinning.