Abstract
Nutritional research has recently emphasized the role of nutrients on gene expression and regulation. Although not as broadly appreciated, availability of nutrients affects gene expression. The response to a nutrient status seems in many cases to be specific for each genotype and specific nutrient impairment results in altered gene expression, depending on each genotype. Recent literature has suggested that carbohydrates, fatty acids, minerals, and vitamins of all the dietary constituents participate in the regulation of gene expression. Here, we summarize the current knowledge on the role of nutrients on cancer, phenylketonuria, cardiovascular and other life threatening diseases.