ABSTRACT
The effects of grape juice consumption on oxidative stress, inflammation, physical performance, muscle damage, and recovery in physical activity practitioners were evaluated in clinical studies. However, to date, no studies have gathered these findings. Thus, we aimed to review all randomized clinical trials (RCTs) that evaluated the effects of grape juice consumption on these markers. The searched databases were MEDLINE/PubMed, Embase®, and Cochrane Central, considering an exhaustive search in the literature with keywords uva OR vitis. The PRISMA guideline was used to conduct and report the review. Seven RCTs with athletes (n = 3), recreational sportspeople (n = 3), and low-intensity physical activity practitioners (n = 1) were included. The qualitative results of the individual studies were controversial, and according to the meta-analysis, acute or chronic consumption of 10/ml/kg/day or 400 ml of grape juice improved antioxidant status but had no effects on markers of oxidative stress, inflammation, physical performance, muscle damage and recovery in physical activity practitioners.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Availability of data and materials
Data are available upon request.
Authors contributions
DBB and LMV designed the study. DBB, LMV, and AS selected and reviewed the articles, extracted the data and assessed the risk of bias. DBB, LMV, AS, DJRG, CWS, FARB, and JB analyzed and interpreted the data, wrote the manuscript and approved the final version.