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Developmental Neuropsychology Volume 46, 2021 - Issue 8
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Research Articles

Distinct Latent Profiles of Working Memory and Processing Speed in Adults with ADHD

Sophie I. Leiba Department of Psychiatry, University of Illinois College of Medicine, Chicago, Illinois, USA;b Department of Psychology, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, USACorrespondence[email protected]
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Richard D. Keezera Department of Psychiatry, University of Illinois College of Medicine, Chicago, Illinois, USA;c Department of Psychology, Wheaton College, Wheaton, Illinois, USAView further author information
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Brian M. Cernya Department of Psychiatry, University of Illinois College of Medicine, Chicago, Illinois, USA;d Department of Psychology, Illinois Institute of Technology, Chicago, Illinois, USAORCID Iconhttps://orcid.org/0000-0003-2678-1207View further author information
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Lindsey R. Holbrooka Department of Psychiatry, University of Illinois College of Medicine, Chicago, Illinois, USA;b Department of Psychology, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois, USAView further author information
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Virginia T. Gallaghera Department of Psychiatry, University of Illinois College of Medicine, Chicago, Illinois, USAView further author information
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Kyle J. Jennettea Department of Psychiatry, University of Illinois College of Medicine, Chicago, Illinois, USAView further author information
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Gabriel P. Ovsiewa Department of Psychiatry, University of Illinois College of Medicine, Chicago, Illinois, USAView further author information
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Jason R. Soblea Department of Psychiatry, University of Illinois College of Medicine, Chicago, Illinois, USA;e Department of Neurology, University of Illinois College of Medicine, Chicago, Illinois, USAORCID Iconhttps://orcid.org/0000-0003-3348-8762View further author information
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Pages 574-587 | Received 03 Mar 2021, Accepted 22 Oct 2021, Published online: 06 Nov 2021
 
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ABSTRACT

This study examined the neuropsychological profile of patients with Attention-Deficit/Hyperactivity Disorder (ADHD) based on Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) working memory and processing speed indices. We aimed to establish whether distinct ADHD subtypes emerge based on neuropsychological testing and determine whether ADHD subgroups differ based on neurocognitive and demographic factors in 179 adult patients with ADHD. Latent Profile Analysis (LPA) revealed four discrete latent subgroups within the sample, each with distinct patterns of working memory and processing speed. Classes significantly differed in demographically predicted IQ, education, and self-reported depression and anxiety. Results reveal heterogeneity in cognitive performance in adult ADHD.

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No potential conflict of interest was reported by the author(s).

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Funding

The author(s) reported there is no funding associated with the work featured in this article.

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