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Original Articles

The Inhibition of the Hydrolysis of Cephanone by CTAB/n‐C5H11OH/H2O Microemulsion

, &
Pages 763-769 | Published online: 17 Mar 2008
 

Abstract

The hydrolysis of cephanone in water, cetyl trimethyl ammonium bromide (CTAB) micelle, and CTAB/n‐C5H11OH/H2O O/W microemulsion was studied through UV‐VIS absorption spectroscopy. The mechanism of the hydrolysis and the effects of both the acidity of the media and the composition of O/W microemulsion on the hydrolysis were studied. The results show that the hydrolysis rate of cephanone increases with the acidity. Compared with water, CTAB micelle and CTAB/n‐C5H11OH/H2O O/W microemulsion suppress this hydrolysis. The inhibition of the hydrolysis of cephanone by CTAB micelle and CTAB/n‐C5H11OH/H2O O/W microemulsion is related to the location of cephanone in the interphases of CTAB micelles and CTAB/n‐C5H11OH/H2O O/W microemulsion droplets.

Acknowledgment

The work is supported by the National Natural Scientific Foundation of China (No. 20233010).

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