The Relation Between Serum Leptin Levels and Max VO₂ in Male Patients with Type I Diabetes and Healthy Sedentary Males

Abstract

This study aimed at investigating leptin levels in male diabetes type I patients who were on insulin treatment and also healthy sedentary males. The study included 10 male type I diabetes patients and 17 healthy sedentary males. Leptin levels of type I diabetes patients and healthy sedentary males with body mass index (BMI) over 25 kg/m² were evaluated separately. The relation between serum leptin, max VO₂, blood lactic acid levels before and after exercise, and effort durations of participants were investigated. At the end of the tests, no difference was found between leptin levels, max VO₂ values, lactic acid values before exercise, and test durations of male type I diabetes patients and healthy sedentary males (p > .05), whereas lactic acid levels after exercise were found to be lower in healthy sedentary males (p < .05). Leptin levels in the group with BMI above 25 kg/m² were higher than those in the group with BMI below 25 kg/m² (p < .001). It was also seen that max VO₂ values and test durations were higher in the group with BMI below 25 kg/m² (p < .05). In conclusion, leptin levels of male type I diabetes patients are close to those of healthy sedentary males. The increase in leptin levels in both groups is in proportion to the BMI of individuals.

• Leptin
• Leptin and exercise
• Max VO₂
• BMI
• Lactate