BINDING CHARACTERISTICS OF A WATER-SOLUBLE β-CYCLODEXTRIN POLYMER

Abstract

The interaction of 18 commercial pesticides with a water-soluble β-cyclodextrin polymer (BCDP) was determined by charge-transfer reversed phase thin layer chromatography and the relative strength of interaction was calculated. The relationship between the calculated surface parameters of pesticides and their capacity to interact with BCDP was elucidated by stepwise regression analysis. BCDP decreased the lipophilicity of the majority of pesticides probably by the formation of inclusion complexes. Significant quadratic relationships were found between the relative strength of interaction and the polar surface area and polar surface energy of pesticides emphasizing the impact of surface characteristics on the relative strength of interaction. The result suggests that the agrochemical properties (adsorption, uptake, half-life, etc.) of pesticide - BCDP complex may be different from those of uncomplexed compounds resulting in modified effectivity.

ACKNOWLEDGEMENT

This work was supported by the grant OTKA T 023422.