Abstract
It is recognized within the pharmaceutical industry that the chiral nature of biosystems results in enantiospecific drug interactions. As a consequence, analytical methods are required to evaluate the enantiomeric purity of active pharmaceutical ingredients. To meet this demand a plethora of chiral selectors have been made commercially available. The options available for a chiral separation are numerous and can be somewhat overwhelming. This review examines some of the more popular chiral stationary phases available for liquid chromatographic separations, provides some insight into their mechanism for enantiorecognition, and provides examples of pharmaceutical ingredients separations.
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