Advanced search
Publication Cover
Journal of Liposome Research Volume 13, 2003 - Issue 3-4
Submit an article Journal homepage
119
Views
3
CrossRef citations to date
0
Altmetric
Research Article

The Interaction of DMSO with Model Membranes. I. Comparison of DMSO and d6-DMSO: A DSC and IR Investigation

Carla J. Long Department of Blood Research, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
,
Peter J. Hmel Department of Blood Research, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
,
Anthony Kennedy Department of Blood Research, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
,
John G. Quiles Department of Blood Research, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
,
Joseph Seelbaugh Department of Blood Research, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
&
Dr. Thomas J. Reid Department of Blood Research, Division of Military Casualty Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA
Pages 249-257 | Published online: 24 Nov 2003
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

The effect of deuterated solvents on the main phase transition (Tm) temperature of large unilamellar vesicles (LUVs) of 1,2-dipalmitoyl phosphatidylcholine (DPPC) was examined by infrared spectroscopy and differential scanning calorimetry. There was no significant difference in the Tm, ΔH of the main transition, or cooperativity when water was replaced by deuterium oxide (D2O) in the preparation of the vesicles or when dimethylsulfoxide (DMSO) was replaced by hexadeutero-dimethylsulfoxide (d6-DMSO) in either D2O or water. These results provide the necessary advance for further structural, kinetic, and thermodynamic investigations of DMSO interactions with membranes and lipid vesicles.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 1,410.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.