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Original Articles

SYNTHESIS AND PROPERTIES OF NOVEL TRIPHOSPHATE ANALOGUES: RIBONUCLEOSIDE AND DEOXYRIBONUCLEOSIDE (α-P-BORANO, α-P-THIO)TRIPHOSPHATES

, &
Pages 1019-1023 | Published online: 07 Feb 2007
 

Abstract

The first ribo- and deoxyribo-nucleoside (α-P-borano, α-P-thio)triphosphates have been synthesized. The chemical and biochemical properties of adenosine (α-P-borano, α-P-thio)triphosphate and thymidine (α-P-borano, α-P-thio) triphosphate have been investigated.

ACKNOWLEDGMENT

This work was supported by grants 1R01-GM57693-01 from NIH and DE-FG05-97ER62376 from DOE to B.R.S.

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