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Abstract
A DNA-binding peptide was selected from a random peptide phage display library. For competitive elution using the DNA methyltransferase M · TaqI in the selection step, a biotin-labeled duplex oligodeoxyribonucleotide containing the 5′-TCGA-3′ recognition sequence of M · TaqI was employed. Nine of ten phages selected were found to have the same deduced amino acid sequence SVSVGMKPSPRP. The selected phage binds to DNA, as demonstrated in an ELISA.