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Original Articles

SYNTHESIS OF 1-(2-NAPHTHYLSULFONYL)PYRAZOLE-C-GLYCOSIDES

, , &
Pages 469-475 | Received 07 Feb 2002, Accepted 12 Jun 2002, Published online: 31 Aug 2006
 

ABSTRACT

2-Naphthylsulfonylhydrazine was reacted with aromatic aldehydes or aldehydo sugars to give the corresponding hydrazones which undergo Michael addition reactions with malononitrile or ethyl cyanoacetate to form pyrazole derivatives.

ACKNOWLEDGMENT

The authors would like to express their thanks to DANIDA establishment, Denmark, which supports the project “Development of new drugs against Hepatitis” at the Chemistry Department, Faculty of Science, Menoufia University for the laboratory facilities and spectroscopic measurements.

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