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Nucleosides, Nucleotides & Nucleic Acids Volume 24, 2005 - Issue 5-7
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Original Articles

PERYLENE ATTACHED TO DNA THROUGH STIFF OR FLEXIBLE LINKER: DUPLEX STABILITY AND FRET

Mikhail V. Skorobogatyj Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
,
Anna A. Pchelintseva Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
,
Alexei V. Ustinov Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
,
Vladimir A. Korshun Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
&
Andrei D. Malakhov Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
Pages 931-934 | Published online: 15 Nov 2011
 
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Abstract

Two fluorescent nucleosides, 5-(perylen-3-ylethynyl)-2′-deoxyuridine and 5-[(perylen-3-yl)methoxypropyn-1-yl]-2′-deoxyuridine, were incorporated into synthetic oligodeoxyribonucleotides and spectral properties of the conjugates and their duplexes were studied.

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