OXIDATIVE TRANSFORMATIONS OF NUCLEOSIDE FLUORENEMETHYL H-PHOSPHONOSELENOATE DIESTERS

Abstract

9-Fluorenemethyl H-phosphonoselenoate monoester has been used to produce thymidine 3′-O-phosphoroselenoate monoester from which various P(V) derivatives containing multiple modifications at phosphorus were obtained; e.g., thymidine 3′-O-phosphoroselenofluoridate, 3′-O-phosphoroselenothioate, or 3′-O-phosphorodiselenoate monoesters.