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Abstract
A new simple method for the efficient synthesis of β-aryl-α,β-unsaturated amides has been developed. The route involves nickel-catalyzed oxidation of benzyl alcohol, followed by Aldol-type condensation with N,N-dimethylacetamide in one step.
ACKNOWLEDGMENTS
This work was financially supported by the National Natural Science Foundation of China (29972037) and Foundation for University Key Teacher by the Ministry of Education.We are grateful to Dr.Yuan-Jiang Pan for 500 MHz NMR measurements.