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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 16
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Original Articles

HIGHLY STEREOSELECTIVE SYNTHESIS OF NERYLGERANIOL-18-OIC ACID

, , &
Pages 2549-2555 | Received 10 Nov 2000, Published online: 09 Nov 2006
 

Abstract

A stereoselectively total synthesis of nerylgeraniol-18-oic acid from geraniol was described. The key steps were the iodization- rearrangement of 2, 3-epoxy alcohol 4, stereoselective Claisen rearrangement and Horner-Emmons olefination reaction.

ACKNOWLEDGMENT

The project was financially supported by the Nature Science Foundation of China (200720152).

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