ABSTRACT
Phosphinic acid analogues of Gly-Gly, NH2CH2CONHCH2-P(R)O2H (R = Me, Ph, t-Bu), were synthesised by the active ester method from free aminomethylphosphinic acids purified on cation exchange resins. The crystal and molecular structure was determined for Gly–Gly(PPh)·H2O (R = Ph). The results point to similar bond parameters as were found for Gly–Gly and its phosphonic analogue Gly–Gly(P).
ACKNOWLEDGMENT
The work was supported by the Grant Agency of the Czech Republic (No. 203/97/0256) and by a grant of the Universita Karlova (GAUK 243/1999/B, to P.V.). We also thank the Grant Agency of the Czech Republic (No. 203/99/0067, to J. Fábry) for support of access to CCDC.