ABSTRACT
2-Acyl-1-(phenylsulfonyl)indoles (3, 7–9) are prepared in 75–84% yield from 1-(phenylsulfonyl)indoles (1, 5) in one operation by treatment of the latter with s-butyllithium followed by inverse quenching of the C-2 lithioindoles with carboxylic acid anhydrides (6).
ACKNOWLEDGMENTS
This investigation was supported by the National Institutes of Health (GM58601), for which support we are grateful.