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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 32, 2002 - Issue 18
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Original Articles

PREPARATION OF QUINOLINES SUBSTITUTED AT THE 2 OR 3 POSITION BY AN ALKENYL OR ALKYNYL CHAIN

Mohamed A. Fakhfakh Laboratoire de Pharmacognosie, associé au CNRS (BIOCIS), Faculté de Pharmacie, rue J.B. Clément, Université Paris-Sud, Châtenay-Malabry, F-92296, France
,
Xavier Franck Laboratoire de Pharmacognosie, associé au CNRS (BIOCIS), Faculté de Pharmacie, rue J.B. Clément, Université Paris-Sud, Châtenay-Malabry, F-92296, France
,
Alian Fournet Institute de Recherche pour le Développement (I.R.D.), 213 rue La Fayette, Paris, F-75480, France
,
Reynald Hocquemiller Laboratoire de Pharmacognosie, associé au CNRS (BIOCIS), Faculté de Pharmacie, rue J.B. Clément, Université Paris-Sud, Châtenay-Malabry, F-92296, France
&
Bruno Figadère Laboratoire de Pharmacognosie, associé au CNRS (BIOCIS), Faculté de Pharmacie, rue J.B. Clément, Université Paris-Sud, Châtenay-Malabry, F-92296, FranceCorrespondence[email protected]
Pages 2863-2875 | Received 06 Aug 2001, Published online: 18 Oct 2011
 
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ABSTRACT

Quinolines substituted by a functionalized alkenyl or an alkynyl chain, either at the 2 or 3 position, were efficiently synthesized from 2-quinaldehyde and 3-bromoquinoline, respectively.

ACKNOWLEDGMENTS

We wish to thank J.-C. Jullian for NMR experiments.

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