AN EFFICIENT SYNTHESIS OF ω-(2,2′-BIPYRIDYL)ALKYL ALCOHOLS AND THEIR ACRYLATES

ABSTRACT

ω-(2,2′-Bipyridyl)alkyl alcohols were synthesized by treatment of methyl-2,2′-bipyridine with LDA at −78°C followed by the addition of ω-bromoalkyl THP ether and hydrolysis of the resulting THP ether. Furthermore, ω-2,2′-bipyridylalkyl acrylates were obtained by the reaction of the corresponding ω-(2,2′-bipyridyl)alkyl alcohols with acryloyl chloride in good yields.

Keywords:

• ω-(2,2′-Bipyridyl)alkyl alcohol
• ω-(2,2′-Bipyridyl)alkyl acrylate
• Carbon–carbon bond formation using alkylation

ACKNOWLEDGMENTS

This work was supported by Mitsubishi Chemical Corporation Fund and the Ministry of Education, Culture, Sports, Science, and Technology of Japan.