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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 32, 2002 - Issue 22
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Original Articles

SYNTHESIS OF AMIDES FROM ESTERS AND AMINES UNDER MICROWAVE IRRADIATION

Fatima-Zohra Zradni Faculté des Sciences, Laboratoire de Synthèse Organique, Es-sénia, Oran Algerie, BP 1524
,
Jack Hamelin Laboratoire de Synthèse et Electrosynthèse Organiques 3, Université de Rennes I et CNRS, UMR 6510, Avenue du Général Leclerc.F-35042, Rennes I, FranceCorrespondence[email protected]
&
Aicha Derdour Faculté des Sciences, Laboratoire de Synthèse Organique, Es-sénia, Oran Algerie, BP 1524
Pages 3525-3531 | Received 06 Aug 2001, Published online: 22 May 2009
 
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ABSTRACT

Formamide, primary and secondary amines react with esters in the presence of potassium tert-butoxide under microwave irradiation. Substituted amides are formed in yields (generally more than 70%) much higher than under conventional heating.

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