Speedy and Regioselective 1,2-Reduction of Conjugated α,β-Unsaturated Aldehydes and Ketones Using NaBH₄/I₂

Abstract

Synthesis of allylic alcohols from α,β-unsaturated aldehydes/ketones has been achieved in excellent yields utilizing NaBH₄ and iodine. This reducing agent is mild and tolerant to a number of functional groups.

Keywords:

• Regioselective
• 1,2-reduction; α,β-unsaturated carbonyl compounds; NaBH₄/I₂

Acknowledgments

The authors wish to thank CSIR and UGC, New Delhi for funding this piece of research work.