Abstract
2-Pivaloylamino-6-formylpterin (1a) and a series of other important heterocyclic aldehydes (2a, 3a, 4a, 6a, and 7a) have been synthesized in good yield by microwave assisted selenium dioxide oxidation. Interestingly, 2-methylpyrazine gives 2-pyrazinecarboxylic acid (5a) under the similar condition.
Acknowledgments
We thank CSIR, Government of India for financial support and Bose Institute, Kolkata for NMR facility. We also acknowledge the help of Reshmi Mukherjee in our laboratory. We wish to thank Professor Thomas Schrader of Philipps-Universitat, Marburg, Germany for the mass spectrum. A. K. A. thanks CSIR, Government of India for providing him a Senior Research fellowship.