Abstract
Melatonin was prepared from phthalimide by N- and C-alkylation, cyclization, hydrolytic, decarboxylation, and acetylation. The four-pot reactions were carried out on microwave irradiation in good yield with short time.
Acknowledgment
The authors thank Prof. Han-Bao Jiang in the department of Radio Engineering, Sichuan University, for reconstructing the microwave oven.