Advanced search
Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 7
Submit an article Journal homepage
214
Views
23
CrossRef citations to date
0
Altmetric
Original Articles

Synthesis of Kojic Acid Derivatives Containing Phenolic Hydroxy Groups

J. Kadokawa Department of Chemistry and Chemical Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Japan; Department of Materials Chemistry, Graduate School of Engineering, Tohoku University, Aoba 07, Aoba-ku, Sendai 980-8579, Japan Fax: E-mail: [email protected]
,
T. Nishikura Department of Chemistry and Chemical Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Japan
,
R. Muraoka Department of Chemistry and Chemical Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Japan
,
H. Tagaya Department of Chemistry and Chemical Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Japan
&
N. Fukuoka Chemipro Kasei Kaisha Ltd., Chuo-ku, Kobe, Japan
Pages 1081-1086 | Received 11 Feb 2002, Published online: 21 Aug 2006
 
Sample our Physical Sciences journals, sign in here to start your FREE access for 14 days

Abstract

Two kojic acid derivatives (2a and 2b) containing phenolic hydroxy groups were synthesized. The preparation was carried out by the reaction of a kojic acid derivative (3) having a chloromethyl group with phenol derivatives (4 and 7), followed by the subsequent deprotection steps. The first reaction proceeded smoothly in the presence of potassium carbonate in DMF at room temperature. Then, the appropriate deprotection reactions gave the desired compounds 2a and 2b. The structures of 2a and 2b were confirmed by the 1H NMR spectra.

Acknowledgment

We are indebted to Ms. Masa Karasu of our research group for her technical assistance.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 61.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 422.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.