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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 9
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Original Articles

Synthesis and Characterization of 5-Substituted Novel Isoxazolidines Derived from 1,3-Dipolar Cycloaddition of Nitrones with Olefins: Studies of Antibacterial and Antifungal Activities

, &
Pages 1545-1555 | Received 17 Apr 2002, Published online: 16 Aug 2006
 

Abstract

The synthesis, antibacterial and antifungal activities of a novel series of 5-substituted isoxazolidine derivatives [3a,b(i–viii)] were described. The synthesis of title compounds was achieved via a 1,3-dipolar cycloaddition of C-(4-biphenyl)-N-(4-methylphenyl)nitrone, C-(4-biphenyl)-N-(4-chlorophenyl) nitrone with monosubstituted alkenes.

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