Abstract
DBU attacks saccharin derivatives with subsequent rearrangement to give rise to 3-[3′-(1′′-azepin-2′′-onyl)propylamino]-1,2-benzisothiazole-1,1-dioxide 2 after work-up.
Keywords:
Acknowledgment
This investigation has enjoyed the support of Payame Noor University, Iran.
Notes
aMolecular formula C16H21N3O3S (Mr = 335.42), crystal size 0.200 × 0.200 × 0.450 mm3, monoclinic, space group P21/c, a = 8.463(7) A°, b = 16.475 (9) A°, c = 11.835 (7) A°, V = 1646 (2) A°3, Z = 4, D = 1.354 g cm−3, μ(MoKα) = 2.05 cm−1, F 000 = 712.2997 Unique reflections collected on a Rigaku AFC6S sequential diffractometer, 2θmax = 50.0°. The structure was solved by direct methods and H atoms were placed geometrically and allowed to ride on the relevant non-H atom. Refinement coverged to give R = 0.061 and R w = 0.069.