An Efficient One-Pot Synthesis of 2-Hydroxyalkyl Dithiocarbamates

Abstract

In the presence of anhydrous potassium phosphate, epoxides reacted with carbon disulfide and primary or secondary amines in acetone to give the corresponding 2-hydroxyalkyl dithiocarbamates regioselectively in moderate to good yield.

Keywords:

• 2-Hydroxyalkyl dithiocarbamate
• Ring opening of epoxide
• Regioselective reaction
• Anhydrous potassium phosphate
• Carbon disulfide

Acknowledgment

The authors wish to acknowledge the financial support of NSFC (No. 20172006).