Conversion of Alkynes into α,α-Dichloro Ketones and α,α-Dichlorodimethyl Ketals Using Trichloroisocyanuric Acid

Abstract

Trichloroisocyanuric acid reacts with alkynes in the presence of water in acetone or acetonitrile to form α,α-dichloro ketones and in methanol to form α,α-dichlorodimethyl ketals.

Keywords:

• Alkynes
• Oxidation
• Addition
• Ketones
• α,α-Dichloro-ketones, ketals, α,α-Dichlorodimethylketals
• Synthesis
• Preparation

Acknowledgment

HRMS data was provided courtesy of John R. Carney. This research was supported in part by NSF-REU program grants.