Reaction of Oxime Derivatives of β-Diketones and β-Ketoesters with Substituted Hydrazides: Novel Synthesis of Nitroso- N-sulfonyl- and Nitroso-N-substituted Amino Pyridones

Abstract

A novel and efficient method for the synthesis of a new variety of nitroso-N-arylsulfonylaminated pyridones and nitroso-N-substitutedamino pyridones via the reaction of oxime derivatives of β-diketones and β-ketoesters with N-cyanoacetoarylsulfonylhydrazides and substituted cyanoacetohydrazides has been investigated. The synthetic potential of the method is demonstrated.

Keywords:

• N-Amino-pyridones
• N-Sulfonylaminated-pyridones
• Substituted hydrazides
• Nitroso pyridones
• Ketoesters
• Diketones