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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 16
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Original Articles

Convenient Preparation of 3,6-Dialkyl-1,6-dihydro-s-tetrazines

Yaquan Sun Institute of Pharmaceutical Engineering, Zhejiang University of Technology, Hangzhou, P.R. China
,
Weixiao Hu Institute of Pharmaceutical Engineering, Zhejiang University of Technology, Hangzhou, P.R. ChinaCorrespondence[email protected]
&
Qing Yuan Institute of Pharmaceutical Engineering, Zhejiang University of Technology, Hangzhou, P.R. China
Pages 2769-2775 | Received 21 Sep 2002, Published online: 19 Aug 2006
 
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Abstract

1,6-Dihydro-s-tetrazines such as 1, with a large variety of substituents in the 3- and 6-position of the heterocycle, have been synthesized, and due to their homoaromaticities and their potential reactivities, have aroused more and more interests (Sauer, J. 1,2,4,5-Tetrazines. In Comprehensive Heterocyclic Chemistry II; Boultou, A.J., Ed.; Elsevier: Oxford, UK, 1996; Vol. 6, 901; Neunhoeffer, H In Comprehensive Heterocyclic Chemistry I; Katritzky, A., Ed.; Pergamon Press Ltd.: Federal Republic of Germany, 1984; Vol. 3, 545).

Acknowledgment

We are indebted to Zhejiang Province Natural Foundation (No. 200016), Zhejiang Province Science and Technology Bureau (011101937) and National Natural Foundation (20272053) for financial support of this research.

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