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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 18
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Original Articles

Microwave-Assisted Rapid Synthesis of Neurotransmitter Release Enhancer Linopiridine and Its New Analogues

J. S. Yadav Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad, IndiaCorrespondence[email protected]
&
B. V. S. Reddy Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad, India
Pages 3115-3121 | Received 12 Nov 2002, Published online: 17 Aug 2006
 
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Abstract

A neurotransmitter release enhancer linopiridine and its new analogues have been synthesized rapidly in yields from the 1:2 coupling of oxiindole with 4-picolyl chloride hydrochloride on the surface of basic alumina doped with 37% KF under microwave irradiation in solvent-free conditions.

Acknowledgment

BVS thanks CSIR, New Delhi, for the award of fellowship.

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