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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 18
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Original Articles

Improved Selective Reduction of 3-Formylchromones Using Basic Alumina and 2-Propanol

Ramiro Araya-Maturana Department of Organic and Physical Chemistry, Faculty of Chemical and Pharmaceutical Sciences, University of Chile, Casilla, Santiago, ChileCorrespondence[email protected]
,
Jorge Heredia-Moya Department of Organic and Physical Chemistry, Faculty of Chemical and Pharmaceutical Sciences, University of Chile, Casilla, Santiago, Chile
,
Hernán Pessoa-Mahana Department of Organic and Physical Chemistry, Faculty of Chemical and Pharmaceutical Sciences, University of Chile, Casilla, Santiago, Chile
&
Boris Weiss-López Department of Chemistry, Faculty of Sciences, University of Chile, Casilla, Santiago, Chile
Pages 3225-3231 | Received 12 Mar 2003, Published online: 17 Aug 2006
 
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Abstract

Treatment of formylchromones, dissolved in 2-propanol with basic alumina at 75°C, selectively reduces the formyl group with good yields without any activation process of the alumina.

Acknowledgments

This work was supported by FONDECYT Grant N° 1000859, J. H.-M. thanks DAAD for a fellowship.

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