The Ester and Amide Derivatives of 4-(4-Methyl Piperazinomethyl) Benzoic Acid

Abstract

Synthesis of 4-(4-methyl piperazinomethyl) benzoic acid (1) from a commercially available and inexpensive starting material with enhanced yields. This acid (1) is then further used for the synthesis of the ester and amide.

Keywords:

• α-Bromo-p-toluinitrile
• N-Methylpiperazine
• Aminoly-sis
• Sodium methoxide

Acknowledgments

The authors wish to thank the management of Dr. Reddy's Laboratories Ltd., for permission to carryout this work. Cooperation extended by all the colleagues of Structural Chemistry Division of Discovery Research is highly appreciated.