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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 22
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Original Articles

High-Throughput Synthesis of Alkylbenzophenones with Indium Triflate in the Absence of Solvents Using Microwave

Hideko Koshima Department of Applied Chemistry, Faculty of Engineering, Ehime University, Matsuyama, JapanCorrespondence[email protected]
&
Masashi Kubota Department of Applied Chemistry, Faculty of Engineering, Ehime University, Matsuyama, Japan
Pages 3983-3988 | Received 12 May 2003, Published online: 19 Aug 2006
 
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Abstract

A series of alkylbenzophenones were rapidly and efficiently prepared from alkylbenzenes and benzoyl chlorides by Friedel-Crafts acylation catalyzed with indium triflate under solvent-free conditions by microwave heating.

Acknowledgment

This work was supported by grants from the Ministry of Education, Science, Sports, and Culture of Japan.

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