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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 3
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Original Articles

A Regioselective Acylation of N‐Substituted‐4‐Aminoindole. Its Application to the Synthesis of Indolactam V

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Pages 523-531 | Received 14 Aug 2003, Published online: 16 Aug 2006
 

Abstract

Optically active (−) Indolactam V (1) was formally synthesized with the defined stereochemistry through an efficient procedure via bromation‐lithiation in the 3‐position of the indole ring using 2,6‐dinitrotoluene and the aminoacids: D‐serine and D‐valine as starting materials.

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