Abstract
A series of 2‐cyano‐3‐aryl‐3‐(3,4‐dihydro‐1(2H)‐naphthalene‐one‐2‐yl) propionitrile derivatives and 2‐aminopyran derivatives were synthesized by the KF‐Al2O3‐catalyzed reaction of malononitrile with 2‐arylmethylidene‐3,4‐dihydro‐1(2H)‐naphthalenone, 2,6‐biarylmethylidene cyclohexanone, or 2,5‐biarylmethylidene cyclopenanone in DMF at room temperature. The structure of the later was confirmed by x‐ray analysis.
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Acknowledgment
We are grateful to the Foundation of the “Surpassing Project” of Jiangsu Province for financial support.
Notes
aX‐ray crystallography for 5a: Empirical formula C22H18Cl2N2O, F W = 409.29, T = 296(2) K, monoclinic, space group P2(1)/n, a = 13.582(2) Å, b = 8.974(1) Å, c = 16.960(2) Å, α = 90°, β = 103.34(1)°, γ = 90°, V = 2011.4(4) Å3, Z = 4, Dc = 1.352 mg m−3, γ(MoKα) = 0.71073 Å, μ = 0.339 mm−1, F(000) = 848. 1.74° < θ < 25.00°, R = 0.0361, wR = 0.0790. S = 0.876, largest diff. peak and hole: 0.138 and −0.156 e Å−3.