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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 10
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Original Articles

Conventional and Microwave Assisted Hydrogenolysis Using Zinc and Ammonium Formate

, , &
Pages 1831-1837 | Received 01 Jan 2004, Published online: 20 Aug 2006
 

Abstract

The selective deprotection of several N‐Bzl amino derivatives to the corresponding amines and the removal of S‐Bzl and O‐Bzl groups from the protected amino acids with ammonium formate and commercial zinc dust are reported. Many other reducible or hydrogenolysable substituents such as halogens, methoxy, phenol, ester, acid, ethene, and Boc groups are unaffected.

Acknowledgment

The authors wish to thank University Grants Commission, New Delhi, India for financial assistance.

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