Efficient Tetrahydropyranylation of Alcohols and Detetrahydropyranylation Reactions in the Presence of Catalytic Amount of Trichloroisocyanuric Acid (TCCA) as a Safe, Cheap Industrial Chemical

Abstract

Preparation and cleavage of THP ethers of different hydroxy functional groups are easily and efficiently performed in the presence of trichloroisocyanuric acid (TCCA) in the absence of solvent with high yields.

Keywords:

• Trichloroisocyanuric acid
• Tetrahydropyranylation
• Detetrahydropyranylation
• Solvent‐free

Acknowledgment

The authors are grateful for the partial support of this work by the Shiraz University Research Council. The valuable help of K. Amani and S. Ghassamipour for repeating some of the reactions is gratefully acknowledged.