Abstract
A series of 1,3,5‐trisubstituted 1,2,4‐triazoles were synthesized via the intermolecular cyclization of hydrazonyl chlorides with nitriles catalyzed by ytterbium triflate [Yb(OTf)3]. The amount of catalysis was discussed and Yb(OTf)3 could be reused without loss of activity.
Acknowledgments
We are grateful to the National Natural Science Foundation of China (No. 20276072), National Basic Research Program (No.2003CB114400), and National Natural Science Foundation of Zhe Jiang Province (No. 2002095) for financial support.