First Total Synthesis of Desmosdumotin C^†

^†Antitumor agent 242

Abstract

Desmosdumotin C (1), a novel compound isolated from the roots of Desmos dumosus, was synthesized from 2,4,6‐trihydroxyacetophenone (2), confirming the assigned structure of the natural product.

^†Antitumor agent 242

Keywords:

• Antitumor
• cytotoxicity
• desmosdumotin C
• total synthesis

Acknowledgments

This study was supported by NIH Grant CA17625 awarded to K. H. L. Thanks are also due to Grant No. 30271533 awarded to J. H. W. from the National Natural Science Foundation of China.

Notes

^†Antitumor agent 242