Structural Assignments of 1‐(β‐d‐Glucopyranosyl)‐1,2,3‐triazoles by ¹H‐ and ¹³C‐NMR Study

Abstract

The ¹H‐ and ¹³C‐NMR spectra of 1‐β‐d‐glucopyranosyl‐1,2,3‐triazole‐4,5‐dimethyl carboxylate, 1‐β‐d‐glucopyranosyl‐1,2,3‐triazole‐4,5‐dicarboxamide, ‐dialkylcarboxamide‐N‐nucleosides 4–18, and 6‐amino‐4H‐1‐(1‐β‐d‐glucopyranosyl)‐8‐hydroxy‐1,2,3‐triazolo[4,5‐e][1,3]‐diazepin‐4‐one 19 had been studied. Resonance signals and anomeric configurations were assigned by homo‐ and heteronuclear two dimensional methods (DQF‐COSY, HSQC, HMBC, HMQC, ROESY).

Keywords:

• Nucleosides
• 1,2,3‐Triazole
• ¹H‐ and ¹³C‐NMR studies

Acknowledgment

We are indepted to Mrs. A. Friemel, Chemistry Department, University of Konstanz for runnung most of the the 2D‐NMR spectra, and to Professor U. Beifuß, Chemistry Department of the University of Hohenheim (Germany) for taking the 2D HSQC‐NMRspectra.