In vivo chondrogenesis in collagen sponge sandwiched by perichondrium

Abstract

In order to increase the cartilage synthesis of the perichondrium, we combined auricular perichondrium with a collagen sponge as a template (perichondrium-sandwiched collagen sponge) and implanted the assembly as an autograft into the back of rabbits. Microscopic examination revealed that cartilaginous tissue was produced in the collagen sponge and chondrosynthesis was accelerated in the collagen sponge implants in comparison with that in materials containing perichondrium alone.

Keywords:

• Chondrogenesis
• perichondrium
• collagen sponge
• artificial cartilage