Down syndrome with cerebral arteriovenous malformation

Abstract

Down syndrome (DS) or trisomy 21 is one of the most common and best known of all chromosomal disorders. Although major congenital malformations such as those of the heart and gastro-intestinal tract are commonly associated with DS, cerebral arteriovenous malformation with motor neurodeficits is rarely reported. A 2-year-old girl with DS presenting with right-sided hemiparesis and right partial seizures is reported. Computerised tomographic scan of the brain demonstrated features of cerebral arteriovenous malformation.