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Annals of Tropical Paediatrics
International Child Health
Volume 31, 2011 - Issue 2
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Original Article

Menetrier’s disease associated with Helicobacter pylori: three cases with sonographic findings and a literature review

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Pages 141-147 | Accepted 01 Feb 2011, Published online: 22 Nov 2013
 

Abstract

Menetrier’s disease is a rare cause of protein-losing gastropathy characterised by hypertrophy of the gastric folds. Three cases are reported. Helicobacter pylori was detected by culture and CLO test in two cases and on follow-up gastroscopy in the other. The first two patients were given eradication therapy and hypertrophic gastropathy resolved whereas in the third the disease remitted prior to the eradication treatment. Typical sonographic features were thickened gastric wall with preservation of the wall stratification. A review of the literature found eight cases of Menetrier’s disease associated with H. pylori in children and these cases are briefly reviewed. H. pylori infection should be considered in all children with Menetrier’s disease and, if isolated, eradication treatment should be administered.

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